CJC-1295 NO DAC

CJC-1295 NO DAC

CJC-1295 NO DAC is a synthetic analogue of growth hormone-releasing hormone (GHRH), also known as modified GRF 1–29 (tetrasubstituted GRF 1–29). The molecule consists of the first 29 amino acids of human GHRH with four substitutions that increase its resistance to enzymatic degradation. Unlike the DAC version, this form has no Drug Affinity Complex linkage. PeptXBio supplies it as a high-grade laboratory lyophilised powder, ready for in vitro research.

Quality and purity

≥99% purity (HPLC). The powder is a high-grade, analytically verified lyophilisate whose batches have a stable composition and reproducible characteristics, suitable for controlled laboratory conditions.

Specifications

• CAS number: 863288-34-0
• Molecular formula: C₁₅₂H₂₅₂N₄₄O₄₂
• Molecular weight: 3367.9 g/mol
• Peptide chain: 29 amino acids
• Amino acid sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂

Why it is studied

As a GHRH analogue, CJC-1295 NO DAC is studied in in vitro models for its selective binding to the growth hormone-releasing hormone receptor (GHRH-R) – a G protein-coupled receptor expressed mainly on somatotroph cells of the anterior pituitary. Research looks at how receptor activation affects intracellular signalling pathways and the regulation of growth hormone secretion in isolated cell systems. The four amino acid substitutions serve as a model for studying the relationship between enzymatic stability and receptor affinity. This information is provided for research context only and is not an instruction for use.

Reconstitution

For laboratory work, the lyophilised powder is usually dissolved in bacteriostatic water, added carefully down the side of the vial – not sprayed directly onto the powder. The vial is swirled gently until the solution is clear; do not shake. The reconstituted stock solution is kept chilled and used in the system set out in the research protocol.

What you get

• Active substance: CJC-1295 (without DAC, mod GRF 1–29)
• Form: lyophilised powder
• Amount per vial: 10 mg
• Solvent (sold separately): bacteriostatic water

Storage

Keep the unopened vial in a refrigerator (2–8 °C), or in a freezer (−20 °C) for longer storage, protected from light. Once reconstituted in bacteriostatic water, keep it refrigerated and use it within the time set out in your research protocol.

Important

For in vitro scientific research only. Not for use on humans or animals; this is not a medicine, dietary supplement or cosmetic product.