Selank

Selank is a synthetic heptapeptide (amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro) designed as an analogue of tuftsin, a naturally occurring immunomodulatory tetrapeptide. The stabilising Pro-Gly-Pro tail attached to the tuftsin chain protects the molecule from breakdown by peptidases, which is why it is studied in the laboratory as a more resistant, longer-lasting variant of tuftsin. Research models examine its interaction with components of GABAergic and monoaminergic signalling and with tuftsin receptor pathways. This information is provided for research context only and is not an instruction for use.

Under in vitro conditions, Selank is used as a tool to study the mechanisms of neurotransmitter signalling and the immune response. Cell and tissue models (for example, neuroblastoma-derived cell lines) analyse its possible influence on GABAergic interaction, monoaminergic signalling and neurotransmitter-metabolising enzymes. Possible immunomodulatory signals related to cytokine expression and tuftsin receptor pathways, and its effect on the dynamics of neurotrophic factor expression, are also studied. All these observations are limited to laboratory experimental models.

The product is supplied as a lyophilised (dry) powder of ≥99% purity (HPLC). Each vial contains 10 mg of Selank. Before laboratory work, the powder is usually dissolved in bacteriostatic water (sold separately) by gently swirling the vial until the peptide is fully dispersed, without vigorous shaking. It is advisable to note the reconstitution date and the chosen concentration so that the results can be reproduced.

Keep the unopened vial of dry powder in a refrigerator at +2–8 °C, protected from light. A freezer (−20 °C) is suitable for longer storage. Once reconstituted in bacteriostatic water, keep the solution refrigerated and use it within the time set out in your research protocol. Avoid repeated warming and cooling cycles to preserve batch stability and reproducibility.

In neuroscience research, Selank is often compared and combined with Semax, another Pro-Gly-Pro-stabilised peptide (an ACTH(4-7) analogue). In experimental models this pairing is used as a dual-mechanism tool: Selank is linked to GABAergic and monoaminergic signalling, and Semax to the modulation of neurotrophic factor expression, so together they are studied in models of stress–cognition interaction and CNS signalling pathways. The combination is used exclusively in a laboratory setting according to the chosen research protocol, without any dosing recommendations.

Absolutely not. This product is sold exclusively for laboratory research and scientific experiments. It is not intended for human or animal consumption and is not a medicine, dietary supplement or cosmetic product.